![IJMS | Free Full-Text | Three-Dimensional Structural Insights Have Revealed the Distinct Binding Interactions of Agonists, Partial Agonists, and Antagonists with the µ Opioid Receptor IJMS | Free Full-Text | Three-Dimensional Structural Insights Have Revealed the Distinct Binding Interactions of Agonists, Partial Agonists, and Antagonists with the µ Opioid Receptor](https://pub.mdpi-res.com/ijms/ijms-24-07042/article_deploy/html/images/ijms-24-07042-g001.png?1681189964)
IJMS | Free Full-Text | Three-Dimensional Structural Insights Have Revealed the Distinct Binding Interactions of Agonists, Partial Agonists, and Antagonists with the µ Opioid Receptor
![RETRACTED ARTICLE: Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text RETRACTED ARTICLE: Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12964-022-00833-3/MediaObjects/12964_2022_833_Figa_HTML.png)
RETRACTED ARTICLE: Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text
![Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress | eLife Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress | eLife](https://iiif.elifesciences.org/lax/23785%2Felife-23785-fig7-v1.tif/full/,1500/0/default.jpg)
Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress | eLife
![Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design | Scientific Reports Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fsrep30797/MediaObjects/41598_2016_Article_BFsrep30797_Fig2_HTML.jpg)
Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design | Scientific Reports
![Stress-Induced p38 Mitogen-Activated Protein Kinase Activation Mediates κ- Opioid-Dependent Dysphoria | Journal of Neuroscience Stress-Induced p38 Mitogen-Activated Protein Kinase Activation Mediates κ- Opioid-Dependent Dysphoria | Journal of Neuroscience](https://www.jneurosci.org/content/jneuro/27/43/11614/F2.large.jpg)
Stress-Induced p38 Mitogen-Activated Protein Kinase Activation Mediates κ- Opioid-Dependent Dysphoria | Journal of Neuroscience
![Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience](https://pubs.acs.org/cms/10.1021/acschemneuro.9b00195/asset/images/large/cn-2019-00195v_0008.jpeg)
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Putative Kappa Opioid Heteromers As Targets for Developing Analgesics Free of Adverse Effects | Journal of Medicinal Chemistry
![Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes - ScienceDirect Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0021925820556810-gr8.jpg)
Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes - ScienceDirect
![Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment | Semantic Scholar Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/b580128a9f89a98a08a72333526e0903627049c9/7-Figure1-1.png)
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment | Semantic Scholar
![Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling](https://www.science.org/cms/10.1126/scisignal.aai8441/asset/236282b7-67c8-485b-87f5-2c5e8c53b95c/assets/graphic/9_ra117_f1.jpeg)
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling
![Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes - ScienceDirect Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0021925820556810-gr1.jpg)
Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes - ScienceDirect
![Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink](https://media.springernature.com/lw685/springer-static/image/chp%3A10.1007%2F164_2020_431/MediaObjects/500126_1_En_431_Fig1_HTML.png)
Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink
![Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects](https://pub.mdpi-res.com/molecules/molecules-28-00346/article_deploy/html/images/molecules-28-00346-g007.png?1672561695)
Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects
![Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design | Scientific Reports Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design | Scientific Reports](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fsrep30797/MediaObjects/41598_2016_Article_BFsrep30797_Fig1_HTML.jpg)
Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design | Scientific Reports
![Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes - ScienceDirect Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0021925820556810-gr3.jpg)